Japanese schoolgirl Kagome is pulled into a well by a centipede monster and through a 500-year old time tunnel to Japan's civil-war era. She escapes from the well with Inu Yasha, a half-dog demon imprisoned in the well 50 years earlier by the priestess Kikyo. Believed to be the reincarnation of Kikyo, she must reluctantly team up with her predecessor's enemy to hunt down the many shards of the "Jewel of Four Souls".

Sesshomaru is the Yokai son of the great Inu no Taishou. Inu no Taishou was considered a daiyokai which means great yokai thus making Sesshomaru one. He is also the half brother of Inu Yasha and shows contempt to him for that. He desires to become stronger at the expense of others.